Publications (2013-present)

• 14-Membered Macrocyclic Ring-derived Toolbox: The Identification of Small Molecule Inhibitors of Angiogenesis and an Early Embryo Development in Zebrafish Assays. Madhu Aeluri, Chinmoy Pramanik, Lakshindra Chetia, Naveen Kumar Mallurwar, Sridhar Balasubramanian, Gayathri Chandrasekar, Satish Srinivas Kitambi, and Prabhat Arya. Org. Lett. 2013, 15(3), 436-439
• Macrocyclic Glycohybrid Toolbox Identifies Novel Anti-angiogenesis Agents from Zebrafish Assay. Bhanudas Dasari, Srinivas Jogula, Ramdas Borhade, Sridhar Balasubramanian, Gayathri Chandrasekar, Satish Srinivas Kitambi, and Prabhat Arya. Org. Lett. 2013, 15(3), 432-435
• An Intramolecular Heck Approach to Obtain 17-Membered Macrocyclic Diversity and the Identification of Anti-angiogenesis Agent from Zebrafish Study. Madhu Aeluri, Jagan Gaddam, Devarakonda V. K. S. Trinath, Gayathri Chandrasekar, Satish Srinivas Kitambi, and Prabhat Arya. Eur. J. Org. Chem. 2013, 19, 3955-3958
• Tetrahydroquinoline-derived Macrocyclic Toolbox Identifies Novel Anti-angiogenesis Agents and Inhibitors of an Early Embryo Development in Zebrafish Assays. Shiva Krishna Reddy Guduru, Srinivas Chamakuri, Gayathri Chandrasekar, Satish Srinivas Kitambi and Prabhat Arya. ACS Med. Chem. Lett., 2013, 4, 666-670
• A Modular Approach to Build the Macrocyclic Diversity on Aminoindoline Scaffold Identifies Novel Anti-angiogenesis Agents from Zebrafish Assay. Srinivas Chamakuri, Shiva Krishna Reddy Guduru, Sreedhar Pamu, Gayathri Chandrasekar, Satish Srinivas Kitambi and Prabhat Arya Eur. J. Org. Chem. 2013, 19, 3959-3964
• Building a Macrocyclic Toolbox from C-Linked Carbohydrates Identifies Novel Anti-angiogenesis Agents from Zebrafish Assay. Srinivas Jogula, Bhanudas Dasari, Mahender Khatravath, Gayathri Chandrasekar, Satish Srinivas Kitambi, and Prabhat Arya. Eur. J. Org. Chem. 2013, 19, 5036-5040
• Small Molecule Modulators of Protein-Protein Interactions: Selected Case Studies. Madhu Aeluri, Srinivas Chamakuri, Bhanudas Dasari, Shiva Krishna Reddy Guduru, Ravikumar Jimmidi, Srinivas Jogula and Prabhat Arya. Chem. Rev. 2014, 114, 4640-4690 (for a theme topic: Chemical Biology of Protein-Protein Interactions; Guest Editor: Prabhat Arya)
• The Prevention of Mitochondrial Membrane Permeabilization and Pancreatic b-Cell Death by an Enantioenriched, Macrocyclic Small Molecule. Ravikumar Jimmidi, Govardhan K. Shroff, M. Satyanarayana, B. Ramesh Reddy, Jahnavi Reddy, Mithila A. Sawant, Sandhya L. Sitaswad, Prabhat Arya and Prasenjit Mitra. Eur. J. Org. Chem. 2014, 1151-56
• Passion for Chemical Biology - Introduction to Dr. Prabhat Arya, Journal from Takshila Publishers, Chemical Biology and Cell Signalling, 2014, March 12, Vol 1, 1-3.
• Rethinking Drug Discovery. Invited article for Magazine, Pharma Focus Asia. Subhadraw Dravida and Prabhat Arya. 2014, Vol 21, Nov Issue.
• A Divergent Approach to Building Latrunculin Family-derived, Hybrid Macrocyclic Toolbox. M. Aeluri, M.; B. Dasari, P. Arya. Org. Lett. 2015, 17(3), 472-475.
• Practical Stereoselective Synthesis of Eribulin Fragment toward Building a Hybrid Macrocyclic Toolbox. Ravikumar Jimmidi, Shiva Krishna Reddy Guduru and P. Arya. Org. Lett. 2015, 17(3), 468-471.
• Stereoselective Synthesis of Rapamycin Fragment to Build a Macrocyclic Toolbox. Shiva Krishna Reddy Guduru, Ravikumar Jimmidi, Girdhar Singh Deora and Prabhat Arya. Org. Lett. 2015, 17(3), 480-483.
• Selected Hybrid Natural Products as Tubulin Modulators. Invited mini-review article. Bhanudas Dasari, Ravikumar Jimmidi and Prabhat Arya. Eur. J. Med. Chem. 2015, 94, 497-508 (special issue on "novel chemistry for undruggable targets").
• A Regio- and Stereocontrolled Dieckmann Approach to Treprostinil-Inspired, Polycyclic Scaffold For Building Hybrid Macrocycles. Srinivas Chamakuri, Srinivas J. and Prabhat Arya. ACS Comb. Sci. 2015, 17, 437-441.
• Stereoselective Synthesis of C27-C35 Eribulin Fragment for Building A Macrocyclic Diversity. Saidulu Konda, Naveen Kumar Mallurwar, Mahender Khatravath, Pallavi Rao, Shivashankar Sripally, Javed Iqbal and Prabhat Arya. Synthesis (special topic: target oriented synthesis of complex molecules) 2016, 48, 1663-1683.
• Macrocyclic Toolbox from Epothilone Fragment Identifies A Small Molecule Showing Molecular Interactions with Actin and Novel Promoters of Apoptosis in Patient-derived Brain Tumor Cells. Bhanudas Dasari, Jagan Gaddam, Temesgen Fufa, Madhu Aeluri, Girdhar Singh Deora, Frank Gaunitz, Satish Srinivas Kitambi and Prabhat Arya. Asian JOC 2016, 5, 976-980
• Geldanamycin-Inspired Compounds Induce Direct Trans-differentiation of Human Mesenchymal Stem Cells to Neurons. Srinivas Jogula, Anand Soorneedi, Jagan Gaddam, Srinivas Chamakuri, Girdhar Singh Deora, Ranjith Kumar Indarapu, Subhadra Dravida, and Prabhat Arya. Eur. J. Med. Chem., 2017, 135, 110-116.
• A small molecule inhibitor of Bax and Bak oligomerization prevents genotoxic cell death and promotes neuroprotection. Xin Niu, Hetal Brahmbhatt, Philipp Mergenthaler, Zhi Zhang, Jing Sang, Wibke Diederich, Eve Wong, Weijia Zhu, Justin Pogmore, Jyoti P. Nandy, Maragani Satyanarayana, Ravi K. Jimmidi, Prabhat Arya, Brian Leber, Jialing Lin, Carsten Culmsee, Jing Yi and David W. Andrews. Cell Chemical Biology, 2017, 24, 1-14.
• Synthesis and Biological Evaluation of Rapamycin-derived, Next Generation Small Molecules. Shiva Krishna Reddy Guduru and Prabhat Arya. MedChemComm, 2018, 9 (1), 27-43.